Brett, A: TH Gene Expression RegulationFemale Rats by Clonid

The study of the expression of the Tyrosine hydroxylase gene was important to analyze its role in the development of hypertension.In WKY and SHR/y female rats there was no difference in the level of expression of Th gene either in brainstem or adrenal gland.Even in treated and control groups no difference was observed.The adrenal gland showed significantly higher levels of mRNA compared with brainstem.Both strains responded similarly to clonidine treatment.When comparing levels of Th gene with BP, Th gene showed no difference between strains or ...