Alam, S: Formulation and Evaluation of Berberine Nanogel

The present study aims to develop and evaluate the permeation as well as anti-microbial activity of developed nanogel of berberine. The incorporation of berberine inside a nanogel should improve berberine stability and permeability. Berberine is a natural polyphenolic agent with promising anti- inflammatory and anti-microbial activity. However, the therapeutic efficacy was challenged in clinical trials mostly due to its low solubility. We design berberine loaded carbopol-934 nanogel to make it stable and substantially enhances cellular permeabi ...